Direct and indirect cellular effects of aspartame on the Brain European Journal of Clinical Nutrition 2008

This article ran in the European Journal of Clinical Nutrition and shows the direct and indirect effects of aspartame, and its metabolites, on the brain. There is much debate on the toxicity of Aspartame, with the FDA and the drug company that made this peptic ulcer drug turned sweetener on one side and literally 100s of biochemical studies showing this substance to be cytotoxic.

Sure, some people can tolerate Aspartame for extended periods of time. Women during the Elizabethan era consumed arsenic as a daily supplement, sometimes for decades (it made the skin pale which was fashionable). However, to suggest that something is not toxic based on such anecdotal evidence is not only junk science but it also directly contradicts the safety standards the FDA has "set" which has resulted in keeping natural sweeteners like Stevia from being sold on the same shelf as sugar.